Imigran 10mg and 20mg Nasal Spray

Each individually sealed Imigran nasal spray contains a single dose of the active ingredient sumatriptan. Sumatriptan belongs to a group of medicines called triptans (also known as 5-HT1 receptor agonists), which are used to treat migraine headache. Imigran works only when a migraine attack has started. It will not stop you from getting an attack. You must not use Imigran to prevent a migraine attack.

Do not use Imigran Nasal Spray:

• if you are allergic (hypersensitive) to sumatriptan or any of the other ingredients listed in the patient information leaflet
• if you have a heart problem such as narrowing of the arteries (ischaemic heart disease) or chest pains (angina), or have already had a heart attack
• if you have circulation problems in your legs that cause cramp-like pains when you walk (peripheral vascular disease)
• if you have had a stroke or a mini-stroke (also called a transient ischaemic attack or TIA)
• if you have high blood pressure
• if you have serious liver disease
• with other migraine medicines, which contain ergotamine, or similar medicines such as methysergide or any triptan/5-HT3 receptor agonist (medicines which are also used for treating migraine)
• with anti-depressants called MAOIs (monoamine oxidase inhibitors), or if you have taken these medicines in the last 2 weeks

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

• ergotamine also used to treat migraine, or similar medicines such as methysergide - don’t use Imigran at the same time or if you have recently taken these medicines
• other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also used to treat migraine - don’t use Imigran at the same time or if you have recently taken these medicines
• SSRIs (Selective Serotonin Reuptake inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake inhibitors) used to treat depression - using Imigran with these medicines can cause serotonin syndrome
• MAOIs (monoamine oxidase inhibitors) used to treat depression - don’t use Imigran if you have taken these in the last 2 weeks
• St John’s Wort (Hypericum perforatum) - taking herbal remedies that contain St John’s Wort while you are using Imigran may make side effects more likely

• unpleasant taste
• feeling sick (nausea) or being sick (vomiting)
• tiredness or drowsiness
• dizziness, feeling weak, or getting hot flushes
• temporary increase in blood pressure
• shortness of breath
• aching muscles

Rest and simple painkillers containing paracetamol, anti-inflammatory drugs (NSAIDs) and aspirin. Some patients report that resting in a darkened room can also bring relief.