Circadin 2mg

Buy Circadin to prevent jet lag

Circadin is a tablet form of the hormone melatonin. Melatonin is secreted naturally by the pineal gland in your brain as your eyes register the fall of darkness. At night, melatonin is produced to help our bodies regulate our sleep-wake cycles. By taking this hormone in a tablet form it can help your body adapt to your new destination's local time quicker.

All our products are genuine UK medicines and are dispensed by our partner pharmacy based in the UK.

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  • Prolonged release melatonin tablets
  • Registered for short term treatment of insomnia and widely used to treat jet lag
  • Not for continuous use longer than five days
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The active ingredient in Circadin is melatonin, which belongs to a natural group of hormones produced by the body. It is usually used for the short-term treatment of insomnia in patients over 55 years of age. It is also commonly used to treat the symptoms of jet lag, but on an unlicensed basis.


You should only take this treatment if you have travelled to another country with a time difference of more than 3 hours.

Do not take Circadin:

  • if you are allergic (hypersensitive) to melatonin or any of the other ingredients listed in the patient information leaflet
  • if you suffer from liver or kidney problems
  • if you have been told by your doctor that you have an intolerance to some sugars
  • if you have been told you suffer from an autoimmune disease (where the body is ‘attacked’ by its own immune system)
  • if you are pregnant, think you may be pregnant, trying to become pregnant or are breast-feeding
Important Interactions

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

  • fluvoxamine (used for the treatment of depression and obsessive compulsive disorder)
  • psoralens (used in the treatment of skin disorders e.g. psoriasis)
  • cimetidine (used in the treatment of stomach problems such as ulcers)
  • quinolones and rifampicin (used in the treatment of bacterial infections)
  • oestrogens (used in contraceptives or hormone replacement therapy)
  • carbamazepine (used in the treatment of epilepsy)
  • antidepressant medication
  • tryptophan
  • alcohol
  • benzodiazepines and non-benzodiazepine hypnotics (medicines used to induce sleep such as zaleplon, zolpidem and zopiclone)
Side Effects
  • nausea
  • headaches
  • stomach discomfort

Stop taking the Circadin and contact your doctor immediately if you experience any of the following:

  • chest pain or severe chest pain due to angina
  • loss of consciousness or fainting
  • feeling your heartbeat
  • depression
  • visual impairment including blurred vision
  • disorientation
  • vertigo (a feeling of dizziness or “spinning”)
  • psoriasis
Please Note

All medication can cause side effects. We have only listed a few to be aware of. Details of all side effects, including rare side effects to be aware of, are listed in the patient information leaflet (PIL). When completing your medical questionnaire, it is very important that you answer the questions truthfully. This is to ensure your doctor has a full picture of your medical history before prescribing. List all medicines you are already taking, including non-prescription and herbal medicines.


Your body will naturally overcome jet lag. Melatonin is used to accelerate this process.

Looking after your medicine

Do not take medicines after the expiry date stamped on the pack. Keep all medicines out of the reach and sight of children.

Medicines are only intended to be used by the person they are prescribed for. Do not give your prescribed medicine to anybody else, even if they have the same symptoms as you. Medicines can be harmful if used by anybody other than the person they have been prescribed for.

References Circadin 2mg Patient Information Leaflet
British National Formulary: melatonin

Currently within the UK, Circadin (melatonin) is not licensed for the treatment of jet lag. However, clinical evidence shows that melatonin can help with the symptoms of jet lag and it is therefore widely used. Melatonin is a hormone that is produced by a small gland under your brain. It's released in the evening and tells your brain it's time to sleep - this is part of your body clock.

There have been a number of studies to see if taking melatonin supplements can prevent jet lag, but results have been mixed. Available evidence points to a greater benefit the larger the time difference between the two countries visited.

Circadin is only available on prescription in the UK, which means you cannot buy it over the counter at pharmacies. You also cannot buy melatonin supplements in health food shops in the UK. The only safe way to get Circadin is to get a prescription issued following a full doctor assessment. This can be with your regular GP or via an online GP consultation. Circadin is available from Anytime Doctor following a full GP assessment.

Circadin, which contains the active ingredient melatonin, is classed as a medicine I the UK. This means that it is not available to buy without a prescription or over the counter. Whilst it is available to buy over the counter in other countries, in the UK you need to be prescribed melatonin by a doctor.

Whilst the sale of melatonin without a prescription is banned in the UK, you can get it on prescription from your GP. Melatonin and Circadin is only banned from being purchased in regular stores and health food shops. It can still be purchased without a prescription in other countries, but in the UK it is deemed to be a medicine and hence requires you to have a prescription from your doctor.  

Last reviewed & updated  29/05/2020   Authored  05/09/2010

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  1. 1

    Complete a free online consultation

  2. 2

    Choose your preferred treatment

  3. 3

    Prescription issued by a GMC registered doctor

  4. 4

    Medicine delivered the next day