Spedra 50mg, 100mg, 200mg

Buy Spedra for Erectile Dysfunction

Spedra works by helping the blood vessels in your penis to relax. This increases the blood flow into your penis, helping it stay hard and erect when you get sexually excited. It is important to note that Spedra only works if you are sexually stimulated. You and your partner will still need to use foreplay to get ready for sex – just as you would if you were not taking a medicine to help you.

All our products are genuine UK medicines and are dispensed by our partner pharmacy based in the UK.

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  • Contains the active ingredient avanafil
  • Available in 50mg, 100mg and 200mg strengths
  • Can be purchased alone or as part of an ED trial pack
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Spedra contains the active substance avanafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Spedra is a treatment for men who cannot get, or keep a hard, erect penis suitable for sexual activity.


Do not take Spedra:

  • if you are allergic (hypersensitive) to avanafil or any of the other ingredients listed in the patient information leaflet
  • if you are taking nitrate medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate
  • if you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir
  • if you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin
  • if you have a serious cardiac problem
  • if you have had a stroke or heart attack in the last 6 months
  • if you have low blood pressure or high blood pressure not controlled by medicines
  • if you have chest pain (angina) or you get chest pain during sexual intercourse
  • if you have a serious liver or kidney problem
  • if you have loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy - NAION)
  • if certain serious eye problems run in your family (such as retinitis pigmentosa)
  • if you are taking riociguat - used to treat pulmonary arterial hypertension (i.e. high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e. high blood pressure in the lungs secondary to blood clots)
Pregnancy and Breastfeeding

Spedra is not to be used by women

Important Interactions

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

  • alpha-blockers – for prostate problems or for lowering your high blood pressure
  • medicines for an irregular heartbeat (arrhythmia) such as quinidine, procainamide, amiodarone or sotalol
  • antibiotics for infections such as erythromycin
  • phenobarbital or primidone – for epilepsy
  • carbamazepine – for epilepsy, to stabilise your mood or for certain types of pain
  • other medicines that may reduce the breakdown of Spedra in the body (moderate CYP3A4 inhibitors) including amprenavir, aprepitant, diltiazem, fluconazole, fosamprenavir, and verapamil
  • riociguat
Side Effects
  • headache
  • flushing
  • nasal congestion
Please Note

All medication can cause side effects. We have only listed a few to be aware of. Details of all side effects, including rare side effects to be aware of, are listed in the patient information leaflet (PIL). When completing your medical questionnaire, it is very important that you answer the questions truthfully. This is to ensure your doctor has a full picture of your medical history before prescribing. List all medicines you are already taking, including non-prescription and herbal medicines.


Other ED medications include Viagra (Sildenafil), Cialis and Levitra. Alternative treatments to ED medication include treating underlying physical or psychological causes, undergoing lifestyle changes, vacuum devices and surgical intervention.

Looking after your medicine

Do not take medicines after the expiry date stamped on the pack. Keep all medicines out of the reach and sight of children.

Medicines are only intended to be used by the person they are prescribed for. Do not give your prescribed medicine to anybody else, even if they have the same symptoms as you. Medicines can be harmful if used by anybody other than the person they have been prescribed for.

References Spedra 50mg, 100mg, 200mg Patient Information Leaflet
British National Formulary: avanafil
Last reviewed & updated  27/04/2020   Authored  16/09/2009

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