Sumatriptan Tablets 50mg and 100mg

Buy Sumatriptan Tablets for Migraine

Migraine symptoms may be caused by the temporary widening of blood vessels in the head. Sumatriptan is believed to reduce the widening of these blood vessels. Sumatriptan tablets work by stimulating receptors called serotonin receptors found in the brain. The natural substance serotonin normally acts on these receptors, causing blood vessels in the brain to narrow. Sumatriptan mimics the action of serotonin by directly stimulating the serotonin receptors in the brain. This narrows the widened blood vessels and helps to take away the headache and relieve other symptoms of a migraine attack, such as feeling or being sick (nausea or vomiting) and sensitivity to light and sound.

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  • Tablets available in 50mg and 100mg strengths
  • Same active ingredient as Imigran tablets
  • Pack contains 6 tablets
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Each Sumatriptan tablet contains a single dose of sumatriptan. Sumatriptan belongs to a group of medicines called triptans (also known as 5-HT1 receptor agonists), which are used to treat migraine headache. Sumatriptan works only when a migraine attack has started. It will not stop you from getting an attack. You must not use Sumatriptan to prevent a migraine attack.


Do not take Sumatriptan tablets:

  • if you are allergic (hypersensitive) to sumatriptan or any of the other ingredients listed in the patient information leaflet
  • if you have a heart problem such as narrowing of the arteries (ischaemic heart disease) or chest pains (angina), or have already had a heart attack
  • if you have circulation problems in your legs that cause cramp-like pains when you walk (peripheral vascular disease)
  • if you have had a stroke or a mini-stroke (also called a transient ischaemic attack or TIA)
  • if you have high blood pressure
  • if you have serious liver disease
  • with other migraine medicines, which contain ergotamine, or similar medicines such as methysergide or any triptan/5-HT3 receptor agonist (medicines which are also used for treating migraine)
  • with anti-depressants called MAOIs (monoamine oxidase inhibitors), or if you have taken these medicines in the last 2 weeks
Important Interactions

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

  • ergotamine also used to treat migraine, or similar medicines such as methysergide - don’t use Sumatriptan at the same time or if you have recently taken these medicines
  • other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also used to treat migraine - don’t use Sumatriptan at the same time or if you have recently taken these medicines
  • SSRIs (Selective Serotonin Reuptake inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake inhibitors) used to treat depression - using Sumatriptan with these medicines can cause serotonin syndrome
  • MAOIs (monoamine oxidase inhibitors) used to treat depression - don’t use Sumatriptan if you have taken these in the last 2 weeks
  • St John’s Wort (Hypericum perforatum) - taking herbal remedies that contain St John’s Wort while you are using Sumatriptan may make side effects more likely
Side Effects
  • feeling sick (nausea) or being sick (vomiting)
  • tiredness or drowsiness
  • dizziness, feeling weak, or getting hot flushes
  • temporary increase in blood pressure
  • shortness of breath
  • aching muscles
Please Note

All medication can cause side effects. We have only listed a few to be aware of. Details of all side effects, including rare side effects to be aware of, are listed in the patient information leaflet (PIL). When completing your medical questionnaire, it is very important that you answer the questions truthfully. This is to ensure your doctor has a full picture of your medical history before prescribing. List all medicines you are already taking, including non-prescription and herbal medicines.


Rest and simple painkillers containing paracetamol, anti-inflammatory drugs (NSAIDs) and aspirin. Some patients report that resting in a darkened room can also bring relief.

Looking after your medicine

Do not take medicines after the expiry date stamped on the pack. Keep all medicines out of the reach and sight of children.

Medicines are only intended to be used by the person they are prescribed for. Do not give your prescribed medicine to anybody else, even if they have the same symptoms as you. Medicines can be harmful if used by anybody other than the person they have been prescribed for.

References Sumatriptan Tablets 50mg and 100mg Patient Information Leaflet
British National Formulary: sumatriptan

You should start with the lower dose of the tablets. Tablets come in 50mg and 100mg strength. Try 50mg first. The dose of Sumatriptan should be taken as early as possible after the migraine headache has started, though it is also effective if taken at a later stage during the migraine attack.

Last reviewed & updated  24/05/2020   Authored  06/01/2010

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