Duac Once Daily 10mg/g + 50mg/g Gel

Buy Duac Once Daily for Acne

Duac Once Daily Gel is a combination treatment that contains both the antibiotic clindamycin and the peeling agent benzoyl peroxide. Clindamycin stops the bacteria involved in acne from reproducing and benzoyl peroxide reduces blackheads and whiteheads. It also kills the bacteria involved in acne. Duac Once Daily may be recommended if Zineryt was unsuccessful after 8 weeks of use.

All our products are genuine UK medicines and are dispensed by our partner pharmacy based in the UK.

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  • Combination treatment containing topical antibiotic and peeling agent
  • Contains the active ingredients clindamycin and benzoyl peroxide
  • To be considered if single treatments (Differin or Zineryt) have not worked
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Duac Once Daily Gel belongs to a group of medicines known as anti-acne preparations and contains two medicines: clindamycin and benzoyl peroxide. Used together these work by fighting the bacteria that can cause acne, treating existing blackheads, whiteheads, and spots and lowering the number of red, inflamed acne spots. Duac is used for treating mild to moderate acne on your skin.


Do not use Duac Once Daily if you are allergic (hypersensitive) to clindamycin, lincomycin, benzoyl peroxide or any of the other ingredients listed in the patient information leaflet.

Pregnancy and Breastfeeding

There is only limited information about the safety of Duac Once Daily Gel in pregnant women and it is not known whether the ingredients can pass into breast milk. However, when clindamycin is taken by mouth or injection, it may pass into breast milk. You must therefore check with your doctor before you use Duac. Do not use this medicine on your breast if you are breastfeeding.

Important Interactions

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

  • any other acne treatments including antibiotics used on your skin
  • medicated or abrasive soaps and cleansers
  • soaps or cosmetics that have a strong drying effect
  • products which contain large amounts of alcohol or astringents
Side Effects
  • redness
  • peeling
  • dryness
  • headache
  • burning
  • pain
  • sensitivity to sunlight
Please Note

All medication can cause side effects. We have only listed a few to be aware of. Details of all side effects, including rare side effects to be aware of, are listed in the patient information leaflet (PIL). When completing your medical questionnaire, it is very important that you answer the questions truthfully. This is to ensure your doctor has a full picture of your medical history before prescribing. List all medicines you are already taking, including non-prescription and herbal medicines.


Further products available include Zineryt (topical antibiotic), Differin (topical retinoid) and Skinoren (azelaic acid). Epiduo is another combination treatment available including benzoyl peroxide plus a topical retinoid.

Other treatments for more severe acne are also available such as Roaccutane (isotretinoin) and Dianette (a contraceptive pill for women only). These treatments need to be monitored closely and can only be prescribed by your GP or specialist dermatologist.

Looking after your medicine

Do not take medicines after the expiry date stamped on the pack. Keep all medicines out of the reach and sight of children.

Medicines are only intended to be used by the person they are prescribed for. Do not give your prescribed medicine to anybody else, even if they have the same symptoms as you. Medicines can be harmful if used by anybody other than the person they have been prescribed for.

References Duac Once Daily 10mg/g + 50mg/g Gel Patient Information Leaflet
British National Formulary: benzoyl peroxide with clindamycin
Last reviewed & updated  14/02/2020   Authored  24/01/2010

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