Atovaquone/Proguanil Hydrochloride 250mg/100mg

Atovaquone/Proguanil Hydrochloride belongs to a group of medicines called antimalarials. It contains two active ingredients, atovaquone and proguanil hydrochloride. Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite (Plasmodium falciparum) into the bloodstream. Atovaquone/Proguanil Hydrochloride prevents malaria by killing this parasite.

Do not take Atovaquone/Proguanil Hydrochloride:

• if you are allergic (hypersensitive) to atovaquone or proguanil hydrochloride or any of the other ingredients listed in the patient information leaflet
• if you have severe kidney disease

If you are pregnant, do not take Atovaquone/Proguanil Hydrochloride unless your doctor recommends it. Do not breastfeed while taking Atovaquone/Proguanil Hydrochloride, as the ingredients of Atovaquone/Proguanil Hydrochloride may pass into breast milk and may harm your baby.

You must tell your doctor if you are taking, have recently taken or might take other medicines, in particular:

• metoclopramide, used to treat nausea and vomiting
• the antibiotics, tetracycline, rifampicin and rifabutin
• efavirenz or certain highly active protease-inhibitors used to treat HIV
• warfarin and other medicines that stop blood clotting
• etoposide used to treat cancer

• headache
• feeling sick and being sick (nausea and vomiting)
• stomach pain
• diarrhoea

The right anti-malarial you require will depend on where you are travelling to. Anytime Doctor also provides branded Malarone and Doxycycline. Other anti-malarial medicines include chloroquine (also known as Avloclor tablets or Nivaquine syrup) and proguanil (also known as Paludrine). The major disadvantage of these two medicines is that many strains of malaria are now resistant, so the drugs are no longer effective. We therefore do not offer chloroquine and proguanil alone. We also do not offer Lariam (mefloquine).